Natural ventilation can provide fresh air for a building and is one strategy for reducing building energy demand while maintaining or improving indoor air quality. However, there exists uncertainties regarding implications of naturally ventilated commercial buildings with respect to indoor air quality. This presentation summarizes a review of the state of building codes and standards, case studies, and research literature regarding the application of natural ventilation to commercial buildings with specific attention to IAQ objectives, including: i) air pollutants of concern, ii) modeling approaches, iii) prescriptive approaches, and iv) new directions for improving IAQ in naturally ventilated buildings