This paper presents local convective boiling measurements in a micro-fin tube for R448A, R449A, and R452B . An existing correlation was modified to predict multi-component mixtures, which predicted 98 % of the measurements to within ± 20 %. The results showed that refrigerant R452B exhibited the highest heat transfer among the three. For an example case, the heat transfer coefficients for R448A and R449A were roughly between 26% and 48% less than that of R404A; whereas, the R452B heat transfer coefficient was approximately 13% larger than that of R404A.