PRAHA project went beyond building and testing prototypes, with alternative refrigerants, that can work efficiently in high-ambient conditions. This presentation introduces the work and findings for assessing the impact of relevant energy efficiency standards on the process of refrigerant selection, examining the economic factors that could affect the decision of adopting low-GWP alternatives, understanding barriers to ease the technology transfer and facilitate transferring the sound use of alternatives in the air-conditioning industry. The presentation also includes key findings and outcomes about examining how using the district cooling applications can reduce dependency on high/higher GWP alternatives and promote not-in-kind technologies.