With environmental concerns on high global warning potential (GWP) refrigerants used in HVACR industry, Carrier Commercial Engineering participated in the AHRI Alternative Refrigerants Evaluation Program (AREP). This study is to understand the Low GWP refrigerant options available to replace R-410A. A 10 ton Rooftop air conditioning unit was tested evaluating four Low GWP refrigerant candidates. The test consisted of EER and high ambient conditions. The refrigerants evaluated were R-32, R-454B, R-446A and R-447A as well as baseline refrigerant R-410A. The current and future regulations for Low GWP refrigerants, energy efficiency, and operation envelop were considered in the investigation.