Indoor carbon dioxide (CO2) has long been discussed in the context of ventilation and indoor air quality (IAQ), focusing on the impacts of CO2 on building occupants, how CO2 concentrations relate to perception of bioeffluents, the use of indoor CO2 to estimate ventilation rates, and demand control ventilation. While measured indoor CO2 concentrations are rarely close to health guidelines, much confusion has resulted regarding CO2 in ventilation and IAQ standards. This presentation addresses the relevance of CO2 concentrations to these standards based on their relation to indoor bioeffluent levels and odors and to ventilation rates per person.