Servicing with low GWP refrigerants is becoming common in the HVAC&R industry due to the phase out of conventional refrigerants. It is important to follow best practices such as refraining from mixing refrigerants and using the recommended lubricants while considering that HFOs will exhibit a different nature than HFC or HCFC refrigerants. This session covers the impact of common contaminants that may influence the system performance and reliability of some very low GWP refrigerants containing unsaturated molecules such as R-1234yf and R-1233zd(E). In addition, stabilizers which can prevent the deterioration of performance due to contaminants is discussed.